A juvenile has been injured after an altercation in Greenville, South Carolina, according to police.Sgt. Diana Munoz with the Greenville Police Department said at approximately 9 p.m., officers ...

A University of South Carolina student was among the two people killed in a wrong-way crash along Interstate 385 in Laurens ...

Fire crews responded to a call at some office buildings off Woodruff Road in Greenville County Friday morning.

WYFF News 4 in 4 is a weekly mini newscast on social media to keep you informed of the top stories in our area before you ...

And GSK announced Thursday that the FDA had approved its medication gepotidacin, with the brand name Blujepa, as oral tablets to treat urogenital gonorrhea in people, 12 and older who weigh at least ...

A Greenville pickleball facility and a Seneca pottery studio are boosting local businesses, while a Woodruff author's new ...

The town of Highlands, North Carolina, is on alert Thursday after the mayor says threats were called in about an attack at a ...

Officials in Highlands, North Carolina, are asking people to avoid the downtown area due to a shooting threat.

The owners of a dispensary in Anderson, South Carolina, have been charged with trafficking marijuana after a search was ...

Her retirement marks the end of an era for the station and its audience, who have welcomed her into their homes for ...