Black flag down: Microsoft has closed an activation loophole that was widely used by software pirates to run Windows and Office without a legitimate license. The group behind the activation tool has ...

The Task Manager in Windows shows overall resource usage by all the processes and applications running on your computer. That way, you can also check if there are any background processes utilizing ...

Colorectal cancer (CRC) is one of the most common malignant tumors worldwide. Although the use of small molecule drugs or targeted drugs has shown significant efficacy in the treatment of CRC, the ...

The senescence of immune cells has also emerged as a key hallmark of immunological dysregulation and chronic inflammation in autoimmunity. Senescent immune cells are irreversibly arrested in the cell ...

In a sterile laboratory, researchers examine petri dishes containing what could be the key to extending human lifespan. These aren’t experimental stem cells or gene therapies, but rather compounds ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Glioblastomas (GBM) are treated with high ...

Objective: Microglial dysfunction has been previously implicated in the pathogenesis of obesity-induced neuroinflammation and sympathoexcitation, both of which significantly increase the risk for ...

Drugs that selectively kill senescent cells may benefit otherwise healthy older women but are not a 'one-size-fits-all' remedy, Mayo Clinic researchers have found. Specifically, these drugs may only ...

In a recent study published in Nature Aging, researchers investigated whether sodium-glucose co-transporter 2 (SGLT2) inhibitors induce senolysis. Senescent cells, responsible for aging, amass in ...

Researchers from Juntendo University, Japan examine the molecular mechanisms underlying the senolytic or senescent cell removal effects of the the sodium glucose co-transporter 2 inhibitor and its ...