Sequencing diverse populations revealed over 41,000 transcripts missing in Eurocentric references, exposing ancestry bias ...

Due to their repetitive and complex DNA sequences, centromeres have been viewed as the "black boxes" of the genome for decades. Often overlooked in sequencing projects but playing a critical role in ...

The Ancient Egyptian Old Kingdom (2686–2125 B.C.) produced many lasting artefacts—but little DNA has survived. Teeth from an elderly man who lived around the time that the earliest pyramids were built ...

Boston Children's Hospital, along with Broad Clinical Labs and Roche Sequencing Solutions, has demonstrated that rapid genomic sequencing and interpretation are achievable in a matter of hours. This ...

UC Santa Cruz has a long history of pioneering advances in genomics research. The first working draft of a human genome sequence was assembled on our campus in 2000, which has led to enormous leaps in ...

Scientists have revealed parts of the genome that are especially vulnerable to mutations that occur very early on in ...

In a breakthrough that redefines both speed and clinical potential, a new world record for the fastest human whole genome sequencing has been set. Think of all the things that can be done in four ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

Twenty-five years ago today, on July 7, 2000, the world got its very first look at a human genome — the 3 billion letter code that controls how our bodies function. Posted online by a small team at ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...