We tested the following fluorescent dyes for their efficacy in the custom labeling reaction: amino-methyl coumarin (AMCA); diethyl aminomethyl coumarin (DEAC); Cascade Blue; fluorescein isothiocyanate ...

DNA bases have a natural tendency to adhere to one another, a characteristic that has been measured in the context of this study. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy ...

Nucleotides are essential components of a wide range of cellular processes; therefore, the maintenance of these levels through various metabolic pathways is crucial for adequate cellular function. The ...

Transcription factor IIH, or TFIIH, pronounced "TF two H," is a veritable workhorse among the protein complexes that control human cell activity. It plays critical roles both in transcription—the ...

The DNA of some viruses doesn’t use the same four nucleotide bases found in all other life. New work shows how this exception is possible and hints that it could be more common than we think. All life ...

In a creative feat of molecular engineering, scientists have for the first time developed a gene editing tool capable of making targeted, single base pair changes in the DNA of mitochondria. The new ...