Viruses are entities that have to infect other cells in order to replicate. They may have genomes that are made of DNA or RNA. We are still discovering new types of RNA viruses, as shown in two new ...

This article explores how challenges such as sequence optimization, immune activation and off-target effects are being ...

While targeted protein and RNA degradation are hot areas for R&D, the drugs developed so far come with limitations. Now, a new class with broader applications may not be far off. In a study published ...

Spatial RNA medicine combines transcriptomics and RNA therapeutics, mapping gene expression in tissues to enhance precision ...

Endogenous RNA is central to protein control and, ultimately, cellular function. Synthetic RNA is an important tool for biological research and is also offering a new generation of promising ...

Researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT have developed a system that can detect a particular RNA sequence in live cells and produce a ...

Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential for organizing cellular life, yet why some RNAs cluster more readily than ...

Industrialized, small batch, and individual RNA therapeutics become practical with “in-a-box” manufacturing technology.

We’re celebrating 180 years of Scientific American. Explore our legacy of discovery and look ahead to the future. In 1957, just four years after Francis Crick and other scientists solved the riddle of ...