Acinar-to-ductal metaplasia (ADM) is a mechanism needed for regeneration after inflammation or injury ADM is a result of epigenetic silencing of markers of acinar cell identity, activation of drivers ...
Dr. Otis Brawley answers the question: 'Atypical Small Acinar Proliferation?' March 16, 2009 -- Question: What does atypical small acinar proliferation (ASAP) mean? Answer: Atypical small acinar ...
Cisplatin and Etoposide Regimen Is Superior to Cyclophosphamide, Epirubicin, and Vincristine Regimen in Small-Cell Lung Cancer: Results From a Randomized Phase III Trial With 5 Years’ Follow-Up ...
The increase in pancreatic cancer cases is closely tied to high insulin levels. Now, a new study reveals a direct link between high insulin levels, common among patients with obesity and Type 2 ...
Organoids—tiny, lab-grown 3D clusters of cells—are a useful tool for studying organ development, disease, and drug responses. These miniature organs-in-a-dish are powerful, but they’re not perfect: ...
The pancreas, located behind the stomach, manages the energy supply in our body. It does so by secreting proteins (enzymes) responsible for glucose – the body's main fuel – reaching other organs when ...
The pathogenesis of chronic pancreatitis (CP) is complex and involves interactions among different cell types, including pancreatic acinar, ductal and stellate cells (PSC). Researchers from ...
(A) Representative H&E staining image of a mouse pancreas. The black arrow denotes the acinar cells and the white arrow denotes the islet. (B) Representative image of electron microscopy analysis of ...
Hans Clevers, PhD, has been working on organoids from the beginning. He was group leader for twenty years at the Hubrecht Institute and has been head of pharma research and early development (pRED) of ...
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